2023

Schmitt LT, Schneider A, Posorski J, Lansing F, Jelicic M, Jain M, Sayed S, Buchholz F, Sürün D (2023). Quantification of evolved DNA-editing enzymes at scale with DEQSeq. Genome Biol. 2023 Nov 6;24(1):254. doi: 10.1186/s13059-023-03097-3. PubMed

Aich M, Ansari AH, Ding L, Iesmantavicius V, Paul D, Choudhary C, Maiti S, Buchholz F, Chakraborty D (2023). TOBF1 modulates mouse embryonic stem cell fate through regulating alternative splicing of pluripotency genes. Cell Rep. 2023 Oct 31;42(10):113177. doi: 10.1016/j.celrep.2023.113177. PubMed

Klotz DM, Schwarz FM, Dubrovska A, Schuster K, Theis M, Krüger A, Kutz O, Link T, Wimberger P, Drukewitz S, Buchholz F, Thomale J, Kuhlmann JD (2023). Establishment and Molecular Characterization of an In Vitro Model for PARPi-Resistant Ovarian Cancer. Cancers 2023, 15(15), 3774. doi: 10.3390/cancers15153774. PubMed

Jelicic M, Schmitt LT, Paszkowski-Rogacz M, Walder A, Schubert N, Hoersten J, Sürün D, Buchholz F (2023). Discovery and characterization of novel Cre-type tyrosine site-specific recombinases for advanced genome engineering. Nucleic Acids Res. 2023 May 9;51(10):5285–97. doi: 10.1093/nar/gkad366. Epub ahead of print. PMID: 37158248; PMCID: PMC10250229. PubMed

Donato E, Correia N, Andresen C, Karpova D, Würth R, Klein C, Sohn M, Przybylla A, Zeisberger P, Rothfelder K, Salih H, Bonig H, Stasik S, Röllig C, Dolnik A, Bullinger L, Buchholz F, Thiede C, Hübschmann D, Trumpp A (2023). Retained functional normal and preleukemic HSCs at diagnosis are associated with good prognosis in DNMT3AmutNPM1mut AMLs. Blood Adv. 2023 Mar 28; 7(6): 1011–1018. Published online 2022 Dec 5. doi: 10.1182/bloodadvances.2022008497. PubMed

Okonechnikov K, Camgöz A, Chapman O, Wani S, Park DE, Hübner JM, Chakraborty A, Pagadala M, Bump R, Chandran S, Kraft K, Acuna-Hidalgo R, Reid D, Sikkink K, Mauermann M, Juarez EF, Jenseit A, Robinson JT, Pajtler KW, Milde T, Jäger N, Fiesel P, Morgan L, Sridhar S, Coufal NG, Levy M, Malicki D, Hobbs C, Kingsmore S, Nahas S, Snuderl M, Crawford J, Wechsler-Reya RJ, Davidson TB, Cotter J, Michaiel G, Fleischhack G, Mundlos S, Schmitt A, Carter H, Michealraj KA, Kumar SA, Taylor MD, Rich J, Buchholz F, Mesirov JP, Pfister SM, Ay F, Dixon JR, Kool M, Chavez L (2023). 3D genome mapping identifies subgroup-specific chromosome conformations and tumor-dependency genes in ependymoma. Nat Commun. 2023 Apr 21;14(1):2300. doi: 10.1038/s41467-023-38044-0. PMID: 37085539; PMCID: PMC10121654. PubMed

Rojo-Romanos T, Karpinski J, Millen S, Beschorner N, Simon F, Paszkowski-Rogacz M, Lansing F, Schneider PM, Sonntag J, Hauber J, Thoma-Kress AK, Buchholz F (2023). Precise excision of HTLV-1 provirus with a designer-recombinase. Mol Ther. 2023 Jul 5;31(7):2266-2285. doi: 10.1016/j.ymthe.2023.03.014. Epub 2023 Mar 17. PMID: 36934299; PMCID: PMC10362392. PubMed

Mircetic J, Camgöz A, Abohawya M, Ding L, Dietzel J, Tobar SG, Paszkowski-Rogacz M, Seidlitz T, Schmäche T, Mehnert MC, Sidorova O, Weitz J, Buchholz F, Stange DE (2023). CRISPR/Cas9 Screen in Gastric Cancer Patient-Derived Organoids Reveals KDM1A-NDRG1 Axis as a Targetable Vulnerability. Small Methods. 2023 Jun;7(6):e2201605. doi: 10.1002/smtd.202201605. Epub 2023 Mar 12. PMID: 36908010. PubMed

Schönberg P, Ding L, Buchholz F (2023). Genom-Editierung ohne die DNA-Sequenz zu verändern – geht das? BIOspektrum. 2023 Jan; 46-48. doi: 10.1007/s12268-023-1882-2. Springer link